The Cytology-Evaluator is meant to assist the cytologist, pathologist and screeners in the evaluation of IHC-stained cervical smears or other cytology specimens, such as urine.
The combination of fast scanning abilities with supreme image analysis permits the identification and morphological evaluation of specific dysplastic, suspicious cells.
The resultant candidates are nicely ordered on an image gallery, where they can be examined by the user and, if so desired, to be re-visited automatically and re-assessed under the microscope.
Automatic definition of the specimen region on the Thin Prep slide is followed by a low magnification scanning, meant to isolate the suspicious cells, based on their color (DAB – brown staining) and morphological parameters.
Non-specific staining candidates are then removed by leaping through the list of candidates, re-evaluate their morphological, and color (hyper-chromaticity) parameters. Depending on the staining quality and other factors, the “Sensitivity-Specificity Slider” (S3 ™) allows the user to define whether they give priority to sensitivity or specificity.
By the end of the process, the user is presented with an image gallery, along with cell locations on the slide, to be accompanied by the "score" given to the specific cell, according to its degree of dysplasia. The results may be sorted by this degree so that the most dysplastic cells are displayed first.
The dysplastic cells are detected and evaluated using low magnification. These cells are being recaptured and reevaluated using higher magnification in order to make sure the degree of dysplasia was calculated accurately.
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The over all statistics for the sample under scrutiny is then displayed along side with the spatial distribution on the slide.
The user, who may include individual cell images in which all the statistics are incorporated, and readily produces case reports.
The data themselves are saved into ASI database – the "Case Data Manager" and can be transferred to review stations for additional examination, documentation, or archiving.
The Cytology-Evaluator may be run in three different modes: Automatic, semi-automatic and manual.
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